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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8de54d16473d40d085f29e2ca3b49e8a2c80b1a48f8491268c841a1189e14452' 
  AND token = 'JYLUotQf+7Vq7HWnSsw3bLe2Ju8m9tLJ90b7D0bB+Z4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}