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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1e33017c482dc90c3845c35046456e69dae1c122a10cb7269ce1157eebcbc01' 
  AND token = 'Zuysrf1j5bsApZLfi0gKAHT98KcuBoG1dTg2SWv0uxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}