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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ed108f1807727e608d2f571f82e391f49523e6d60f965287b844abc39f7df49' 
  AND token = 'ASgRdQs9RF03aUho6UOfFcsWriH3i8Ai1u5g09eLeGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}