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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0b1187717f8bfa6b132b2196374b7376baeeb0f8e48d153057e21b15bd6250f' 
  AND token = 'tU/9vVLluVpPalqJyjSY7Zj3VZ10DO4/5GRPJ4Jc0eY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}