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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d85989a77cd9c580dc21ab80f65b3cd1820a08c4e95ebf52b60a38236fb4acc' 
  AND token = 'zlorwqMRyeqStA9wunxsjb6OEXSAudDaFLhzAdXhkW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}