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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd36d998c6294ae1e058784f35bdbe501c62273d943cd7f316ebebbd11450625c' 
  AND token = 'u0kPA4taKPt03a+ZIGrwVD5kpF/IXmwV30wR6jUiB/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}