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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '90e8d251a467d1b88b9035af3c132953ed8b238f15d19e3b1a77eeab68dd7b60' 
  AND token = 'x5SxzTN0j7P5uVmH0QAAIrpUBDXtSGFtNZFfBzU/GOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}