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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8365f55c9224d9ea31c32198589dbbd3c70707b3f545e6433d77757b6651f3d' 
  AND token = 'kpvEf8hx1k3fAhpPRCC2vM+zGfIhkk823c4GeIfKrK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}