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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5625f0f3cc75f51714a2ba5b6d2312c9a82f8c1f9e51010668f8d222cb311a64' 
  AND token = 'lYvKm0B2RfcgWjEdXQUopj/srxDWD7ZTyh8Q+1IRSaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}