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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a731d08bbe1a6c96636cd8ba6ec30d94de33490a18b08d43509212290d0a610' 
  AND token = '8oAFkDoGoOnffvYLTp1aZIsitEqjzGtsZd4o9zsW+v8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}