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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cf43317c5bd3b99337a8acb0e57dcf4b98eaca7a2356b35dae17c224605b612' 
  AND token = 'HWPgNgUTix0R4ESTZ6CTl18V1FEe3wIXuYkae/oPoOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}