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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '025a035645091fa0b9e7ed0210a8b6826f4fb56900a5ac4d8237b57898a994d3' 
  AND token = 'DCv7uVd8kGxIOLWWp2cP2QiFGl3ftPGf0odfcOsxg2w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}