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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28527ac30a4214104a964f29586a28ffa78ba7ec88b5bf856b3020c5c31b47f6' 
  AND token = 'IzXlrxDBAj8Qf49mVCQdWEe27v3c62zMNJGWnAhUTPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}