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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25a8aff5077e54d7e9a0ee83a844d2f9867056f861aecd326fd26d76a2b61321' 
  AND token = 'QgardMBxkP8WWBLmFlttu7KWk47W9clNz1pp+uZiPiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}