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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3477d8fc3d8c926290eec05dc2b0499e562ec400d42c8606022cb3530f58539' 
  AND token = 'D7RBDxKApOZN5w1DIZZiv6oMKVnmWaVEiJVy7Igss/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}