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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d3e77796d4da0b43e2e30639880e14e7c65996a0d75cd549a9806bc7f2e44e6' 
  AND token = 'zL1Sb1/UbC2yt4YDNk9Iwc0H3YOmqYoEqC4e0Cph294=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}