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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21af2937935a105f7984ad654ddf42d601111b07b9c2c3d18554dd099e62369b' 
  AND token = 'dPsygmxAN6WkIowSBb9N942xnuGJ/hrAZ3+pK5Rrwro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}