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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73ff779b27a45ed5694c02152391d38b4d261b8d0b2b0168edfd2bbb96b62ec8' 
  AND token = 'TDHCcvozsN3iR6Hrx7dXj0iGq57ZlqbX4uOqNnWztEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}