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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c177166bb4925a110f27151d85d6d9742916231b19a4528a457b94f87d2532d1' 
  AND token = 'CEcWZy3gO3xW6q14577iexi0ZOUy+SYbfZf2kHJKDzk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}