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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffc14c47c45ee1336681420eac4a8066f6bfdc852cbe451006353cd70d2f78a8' 
  AND token = 'sZC+UpAr5jRV+Q8HnbmRUgFKgISH62S87Ngm6qZ+s4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}