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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bce9e10d3d9071e11acc707b1dd7d518dc99b59fe80f3e1842f65c1f0e8c09e2' 
  AND token = 'kF+gzHxx0sVopYhfCskqGOUD6ss9y9Xx6wIkGG7tW1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}