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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f1a3faabfc0716c1bf6ae64793e9bb74d000014029f0d45fdeba37a85e31bd7' 
  AND token = 'nI8iVFxfMi6jFXJlIjSl3vRUNI9JX1M3AJjOqAj/0jA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}