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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1cf78ce7c782e4fb3efc19c9d615f378bd7e98a146e452ae7f206ba8a996ac0' 
  AND token = '/CxfLsemlPuECGLx0pQt2iHxbSG4F0P1XMZchbALbFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}