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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '005987cf563dcef8eb95ef91e217851ed521b2c47ccbd2e5e767af8214c8daaf' 
  AND token = 'VNmfFmVqEGkYYSERq/qNcQDjHMDy3YZ1vlWIVdy4W5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}