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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e9dc146cf6dfb540e3f37dc21b58a8d20b892d95b084c36b1f62dff236ab720' 
  AND token = 'Sa2h7mlJBaViJCi62txQKMD33+mk4l6Hr8OAAsAdguY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}