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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45094a9a186e83708fe303e03f865dc7320ae23f6cb99cc839e0cf0c77b112de' 
  AND token = 'MwXzzIPfurkkG0rVSxo/a9gYLhZXzltTcLrtoHUePIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}