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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f3b7b6c817e7c6b218a91d8994a3ae0a58faf31459477dfa7696a7b46fc14ec' 
  AND token = '2uUR0+FkmHLmavLtJaJ7HGODdVGIU2QlIDD52DVc6vo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}