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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a09c41f85e9e6f6ffc825b5bfbdd19baa2579c303b92ab83cce8abee6e4e87ad' 
  AND token = 'aZdbyUc+8Nu7EPUokea19u7ZshsZKRKVs0qGmHKr5Fw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}