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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a0734a8160620a468a30e896890db629d06c437d1e9c56a873329092b80c292' 
  AND token = 'pRMYsUrPCvfKWAV9NdsKK9PrADS+6Nuf3MsqxPwhdT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}