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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22aa149784eda3a01f3163281297ebe4dc4d06cddc26c862192a0bb0d1638448' 
  AND token = 'VPTsE18j53Vn9ug8Id2ObHLqaUaqjocvkWi7XNBFYL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}