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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08cc70eed0c8b6a0969a0ab1752f18ed89fa67ec61865adabf35ccc7aa40b073' 
  AND token = 'jhB++bhHVnjgrd9nfn7RaqTZrN2JqdTxPAc3GN6ib0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}