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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25946def69be01a2246fad5f3be62e837f4af447775cad8f44a4196bf64926c1' 
  AND token = 'F/af1P6obGn5FBk4tD3IE4mOXs+PPZ3rW8VsM13Q4iM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}