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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fb548c7d92fdde9dd8a52ff026a0fab076aa6edd6aee3b67b29b504b3120fbb' 
  AND token = 'MeInfNYLQW+kvWB+Z855E/Tp3TdQhtWXGjv7xnTkWOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}