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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc048d67672c6e995a715615cd4492e2eeda1f763049677e897ee27561784801' 
  AND token = 'ZwlHYq8Js+1FykDL4xcHhuOUlR9S/DFk2vbTdWEzhyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}