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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85d75bb1ede2772b25115ca5a7993bfd380bd3ab4d26bf5c5e928a04096005f6' 
  AND token = 'zRPMdTA0dPbZbvC547lq8xHPyQubEfLSpHZ1ByAvNtg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}