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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d6461d0fee79f4276ff2353857d1849e7a51fd836b3406a21ad807a301a3ed7' 
  AND token = 'eg0EAgOaUU5r82HY7tbbzLeUoqSohx8kkR5VlUHkizU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}