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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe70d466d843c023f880e42debbf38fb2a5f34c8c4301b5e49022a8d45aec4d5' 
  AND token = '01yVf6RDhzOrUlDadK2x6wvWLE0TUm2cq9YT7ojdm6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}