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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72bd9e2283f692a6c253f508d555516f2e86321a015f1d6e2ba35beae9413aa2' 
  AND token = 'T3EBUmY6FF2MmeoaPp3XXoNKNq2xocH+BwLVQJSmyDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}