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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '538b3314def08b59e8da0227fe32f272130027dd7b602c4480bb95351e87a265' 
  AND token = 'DTrU/JGeBN0R3zXNabtegJyAkZDVfnFh5bnvu2mTieA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}