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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8621c71d050087255b62ae014c9fd17b392a620d6192a831683d96295940be97' 
  AND token = 'mASbw16dxkYYDuH0VV4PhqTBnXf7ugafWTNgkx0WyXQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}