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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f93d4f279ea8e9137c976ac292ced898a84f2db070209983c5e9eb9fbd1dd7f' 
  AND token = 'IBK2fPyONir3bZ/TutR0JFhBM3I3F71NXKTbnCi7H5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}