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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2889f0aa090a4c0481e1e26fa4e9a5cadea094c285234480a2fd89b5181a95de' 
  AND token = 'Xt9ZXvqeQjXIIL4HU7bkmDoxKkKNw48VWwvsJolQW4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}