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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce09aa3d002e692643548db1a298f7e819d01ccbd47d3a072df15ddec3522825' 
  AND token = 'sYCwW84ttNgKgxaPtxuK18Pm2wFD53n1g8QMY26AVj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}