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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70b9ef59c97ef7559c392a9e4735e4768bb38f29664419f6841218a9380d20b1' 
  AND token = '/1ZjWb0E2SjEksFFTko87kzUn6jjGoYplSR6L7d6rsQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}