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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2edde383af2b3514bfeb481d700332a195ce0e70f3d5118a5b7c5c20b552eded' 
  AND token = 'PKiD9hZ7tZ2Ockw5ziAOHbeGFsx5WJh8iS18vyx7YGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}