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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3de2a61d67455c76179f5d60132034d5acc1cc086cf9044713da17bfeaa89cf1' 
  AND token = 'cLLKlb+kcqEiLy66JO8cVuE/A3TQsfbg1G9kKiVtC68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}