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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ea5c9a06e4c07eb74d7aff84cc446d44240410b54106417fdfe3c6276fad5fe' 
  AND token = 'jpuppE/NmWD8GbjS3MM3sHyyiZqQh9XTGiWTQKSDyUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}