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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '813e9c871f3683315cad71b6a2a828064341354ffa93372a05ee6cb89bf6d829' 
  AND token = 'TK3Y8C5QPSrOdX7tM+rpus7XPOdWuIIRVXNplfTw5cM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}