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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4733606290a8f7cb83ca3c6f220c733a3bddad8b18971d76015b96d25831b53c' 
  AND token = 'XH5cOQI35nQ86mXEXC6ibC2WKRUOEcR6MoFosvyEfoQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}