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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e1cf693ff8d11798c59d195298867f23f95bdb05f1787d1ffde6f0d7885d7c5' 
  AND token = 'lVdHH5Ctrkielt4RMAXf2VMLQb+SdSYjPCZSK/SfOgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}